Overt hypothyroidism
TSH clearly raised with a low free T4. The classic picture: tiredness, cold intolerance, dry skin, hair shedding, constipation, heavier or irregular periods, and weight that crept up without a change in eating.
An underactive thyroid slows the rate at which the body uses energy, and weight gain is one of its commonest signs. It is also one of the few genuinely treatable causes, which is why it is checked before any plan is made. What treatment does not do is return the weight on its own — it removes the obstacle, and the plan still has to happen.
Identifying the type matters, because each is treated differently.
TSH clearly raised with a low free T4. The classic picture: tiredness, cold intolerance, dry skin, hair shedding, constipation, heavier or irregular periods, and weight that crept up without a change in eating.
TSH raised with a normal free T4. Common, often symptom-free, and genuinely debated as to when it needs treating. Antibodies and symptoms both feed into that decision rather than the number alone.
The commonest cause of an underactive thyroid — the immune system gradually reducing thyroid function. Antibody testing identifies it, and it changes what to expect over the following years rather than what to do this month.
On replacement, TSH in range, and the weight has not shifted. This is a common and frustrating position, and it usually means the thyroid is no longer the whole story rather than that the treatment has failed.
TSH first, with free T4 and antibodies where the picture calls for it. It is a straightforward blood test, and it is the single most useful thing to do before starting any weight plan — because if it is abnormal, everything downstream changes.
Where replacement is indicated it is prescribed and monitored with repeat blood tests, and the dose is settled over months rather than at one visit. It corrects the deficiency. It is not prescribed to change weight, and anyone offering it that way is doing something else.
Energy, cold intolerance, skin and hair usually improve. Weight typically shifts less than people hope — some of what is lost early is retained fluid rather than fat. The obstacle is removed; the plan still has to happen, and it is far more likely to work now.
That is the point to look further rather than to increase the dose. Insulin resistance, a medicine causing gain in its own right, disturbed sleep, or simply a plan that was never built for your routine are the usual findings, and each has its own answer.
This page is about the cause. For what each test shows and when it is worth asking for, see Which blood tests actually matter.
Yes. An underactive thyroid slows the rate at which the body uses energy, and weight gain is one of its commonest signs — usually alongside tiredness, cold intolerance, dry skin and hair shedding. It is one of the few genuinely treatable causes, which is why it is tested before any plan is made.
TSH is the first-line test, with free T4 and thyroid antibodies added where the picture calls for it. It is a straightforward blood test and it is the single most useful thing to do before starting any weight plan.
Usually less than people hope, and some of what moves early is retained fluid rather than fat. Treatment removes an obstacle rather than doing the work — but a plan built after the thyroid is corrected is far more likely to hold than one built before.
That is the point to look further rather than to adjust thyroid treatment. Insulin resistance, a prescribed medicine causing gain in its own right, disturbed sleep and an unsuitable plan are the usual findings, and each has a different answer.
Sometimes, and it is genuinely debated. A raised TSH with a normal free T4 is common and often symptom-free. Antibodies, symptoms and your wider picture feed into the decision rather than the number on its own — which is a conversation with a doctor rather than a rule.
This page is educational and does not replace an in-person consultation. Medical disclaimer · How we write our content